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Monday, April 20, 2020 | History

3 edition of Metabolic and molecular aspects of cardiomyopathy found in the catalog.

Metabolic and molecular aspects of cardiomyopathy

Metabolic and molecular aspects of cardiomyopathy

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  • 9 Currently reading

Published by University of Tokyo Press in [Tokyo] .
Written in English

    Subjects:
  • Heart -- Metabolism -- Disorders.,
  • Myocardium -- Diseases -- Molecular aspects.

  • Edition Notes

    Includes bibliographical references and index.

    Statementeditors, Lionel H. Opie and Tsuneaki Sugimoto ; associate editor, Teruhiko Toyo-oka.
    SeriesCardiomyopathy update ;, 4
    ContributionsOpie, Lionel H., Sugimoto, Tsuneaki, 1932-, Toyo-oka, Teruhiko.
    Classifications
    LC ClassificationsRC687.5 .M48 1991
    The Physical Object
    Paginationvi, 249 p. :
    Number of Pages249
    ID Numbers
    Open LibraryOL1305999M
    ISBN 100860084795, 4130681559
    LC Control Number92173761


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Metabolic and molecular aspects of cardiomyopathy Download PDF EPUB FB2

ISBN: OCLC Number: Description: vi, pages: illustrations ; 27 cm. Series Title: Cardiomyopathy. Diabetic Cardiomyopathy: Biochemical and Molecular Mechanisms is a compilation of review articles devoted to the study on the topic with respect to biochemical and molecular mechanisms of hyperglycaemia.

The wide range of areas covered here is of interest to basic research scientists, clinicians and graduate students, who are devoted to study. Buy Diabetic Cardiomyopathy: Biochemical and Molecular Mechanisms (Advances in Biochemistry in Health and Disease Book 9): Read Books Reviews - High FFA levels, impaired insulin metabolic signaling, and hyperglycemia activate the NLRP3 (NACHT, LRR, and PYD domains-containing protein 3) inflammasome, a novel molecular marker in diabetic cardiomyopathy.

88 Separation from cytoplasmic chaperones and oligomerization follows NLRP3 activation, leading to recruitment of procaspase The present Special Issue will cover deep pathogenesis and molecular and clinical aspects of cardiomyopathies, with specific attention to cellular energetics and metabolic mechanisms, and the development of future targeted therapies, and the specificity of predictors across several behavioral addictions.

Completely revised with 15 new chapters, the book includes coverage of the roles of gut microbiome in obesity and diabetes, macrovascular and microvascular complications, diabetes, metabolic syndrome and kidney disease, aspects of diabetic cardiomyopathy, diabetes, Alzheimer’s and neurodegenerative diseases, roles of SGLT2 inhibitors in the.

Heart failure (HF) affects 1–2 % of the population in developed countries and absorbs a significant amount of human and economic resources. 1–3 It is a complex syndrome, characterised by a spectrum of symptoms and signs ranging from minimal loss of normal functional capacity to more severe symptoms refractory to medical therapy.

It may be Cited by: Biomarkers in Inborn Errors of Metabolism Clinical Aspects and Laboratory Determination Clinical Aspects and Laboratory Determination is structured around the new reality that laboratory testing and biomarkers are an integral Metabolic and molecular aspects of cardiomyopathy book in the diagnosis and treatment of inherited metabolic diseases.

The book covers currently used biomarkers as. The concept of molecular medicine dates back to Linus means that there are many new opportunities and challenges Pauling, who in the late s and early s generalized for clinical medicine. One of the effects of the completion of from the ideas that came from the study of the sickle cell the Human Genome Project is the increasing application of.

Diabetic Cardiomyopathy: Biochemical and Molecular Mechanisms is a compilation of review articles devoted to the study on the topic with respect to biochemical and molecular mechanisms of hyperglycaemia.

The wide range of areas covered here is of interest to basic research scientists, clinicians and graduate students, who are devoted to study Format: Hardcover.

Among the million deaths each year associated with diabetes, about two thirds are attributable to cardiovascular complications, and diabetes is now considered to be a major metabolic risk factor for the occurrence of heart disease. Diabetic Cardiomyopathy: Biochemical and Molecular Mechanisms is a compilation of review articles devoted to.

Good Manufacturing Practices for Pharmaceuticals, Seventh Edition This book provides insight into the world of pharmaceutical quality systems and the key elements that must be in place to change the business and organizational dynamics from task-oriented procedure-based cultures to truly integrated quality business systems that are self-detecting and correcting.

Abstract: Hypertrophic cardiomyopathy (HCM) is a fascinating disease with diverse phenotypic expression that spans from minimal hypertrophy to severe heart failure and sudden cardiac death (SCD).

HCM is the most common cause of sudden cardiac death (SCD) in the young competitive athletes and a major cause of morbidity and mortality in by: In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential.

As new methods of mutation screening emerge, both for the genome and for the “epigenome,” comprehensive. Metabolic cardiomyopathies.

Int J Exp Pathol Article Literature Review in International Journal of Experimental Pathology 81(6) December with 55 Reads. Metabolic and Molecular Aspects of Cardiomyopathy (Cardiomyopathy Update, 4) (v. 4): ISBN () Hardcover, Univ of Tokyo Pr, Founded inhas become a leading book price comparison site.

Metabolic cardiomyopathy is a chronic metabolic disease characterized by structural and functional alterations and interstitial fibrosis without coronary artery disease or hypertension.

Diabetic Cardiomyopathy Estimated delivery business days Format Paperback Condition Brand New Description Diabetes has long been recognized as a disease of high blood sugar, and there has been a continuous search of the exact reason for its development and effective treatment.

Inthe World Health Organization had estimated that more than million. This book provides an analysis of biochemical and molecular mechanisms of cardiac dysfunction in diabetic cardiomyopathy. It contains reviews from leading experts in the area of cardiac dysfunction, and emphasizes molecular, subcellular, and signal transduction mechanisms of contractile dysfunction in chronic diabetes.

Cardiomyopathy is a group of diseases that affect the heart muscle. Early on there may be few or no symptoms. As the disease worsens, shortness of breath, feeling tired, and swelling of the legs may occur, due to the onset of heart failure. An irregular heart beat and fainting may occur. Those affected are at an increased risk of sudden cardiac death.

Causes: Unknown, genetic, alcohol, heavy metals. Hypertrophic cardiomyopathy is characterized by the presence of increased left ventricular wall thickness that is not solely explained by abnormal loading conditions (such as hypertension or valvular disease).

Hypertrophic cardiomyopathy is a genetic disease, usually with an autosomal dominant inheritance. About 35–60% of patients with hypertrophic cardiomyopathy carry a Author: Philippe Charron. The first section discusses general aspects of the metabolic derangements in diabetic cardiomyopathy including metabolic alterations and substrate utilization as well as cardiac remodelling in the heart; role of diet in the development of metabolic syndrome in the heart; effect of hyperglycaemia in terms of biochemical and structural Brand: Belma Turan; Naranjan S Dhalla.

Diabetic cardiomyopathy (DCM) is an independent clinical entity defined as structural and functional changes in the myocardium because of metabolic and cellular abnormalities induced by diabetes, resulting in cardiac failure. Hyperglycemia has been seen as a major cause of DCM due to activation of different mechanisms leading to oxidative stress.

Several body of evidence Cited by: 3. Diabetic Cardiomyopathy: Biochemical and Molecular Mechanisms is a compilation of review articles devoted to the study on the topic with respect to biochemical and molecular mechanisms of hyperglycaemia.

The wide range of areas covered here is of interest to basic research scientists, clinicians and graduate students, who are devoted to study Brand: Springer New York.

The Genomic Medicine Foundation (UK) is a registered non-profit corporate organization providing up to date and evidence-based information on all aspects of OMICS and Genomics relevant to the contemporary practice in clinical and preventive medicine and healthcare.

The Foundation undertakes a number of professional activities including publishing books &. The outlook is almost uniformly fatal, and the few babies who survive have severely compromised development and a cardiomyopathy that usually proves fatal. In rare cases, a patient stays asymptomatic until after the neonatal period, when hepatomegaly, vomiting, metabolic acidosis, hypoglycemia and a proximal myopathy become : Marc Yudkoff.

The title of this book should be the first indication that this is an unconventional book. The book is essentially two books in one. Both parts cover a very large number of pathological entities to varying depths, and the amount of space devoted to a Author: Dennis W Dickson.

Title(s): Metabolic and molecular aspects of cardiomyopathy/ editors, Lionel H. Opie, and Tsuneaki Sugimoto ; associate editor, Teruhiko Toyo-oka. Country of Publication: Japan Publisher: [Tokyo]: University of Tokyo Press, c Metabolism Open is a new, peer-reviewed, fully open-access sister journal to Metabolism, both publishing original research and reviews related to all aspects of human metabolism.

Articles considered for publication include studies in humans, animal and cellular models. Diabetes mellitus increases the risk of heart failure independent of co-existing hypertension and coronary artery disease. Although several molecular mechanisms for the development of diabetic cardiomyopathy have been identified, they are incompletely understood.

The pathomechanisms are multifactorial and as a consequence, no causative treatment exists Cited by: Dilated cardiomyopathy is the most common form of cardiomyopathy and the second leading cause of left ventricular dysfunction with highly variable clinical presentation and prognosis.

The clinical courses vary and are strongly heterogeneous, ranging from asymptomatic patients to those suffering from intractable heart failure or sudden cardiac death due to : Deborah P. Schild, Sascha I. Ricciardi, Jens G. Hellige, Rolf Vogel, Nisha Arenja.

Cardiovascular and Metabolic Effects. In this report, for the first time in the Veterans and Agent Orange series, cardiovascular health outcomes and metabolic effects are being addressed independently of other health outcomes. In previous reports in the series—Veterans and Agent Orange: Health Effects of Herbicides Used in Vietnam, hereafter referred to as VAO (IOM.

Background: Systemic primary carnitine deficiency is an autosomal recessive disorder of the carnitine cycle caused by mutations in the SLC22A5 gene that encodes the carnitine transporter, organic cation transporter.

Systemic primary carnitine deficiency typically presents in childhood with either metabolic decompensation or cardiomyopathy. We report five families in which low Cited by:   Taurine 9 contains original articles and critical reviews based on the oral and poster presentations of XIX International Taurine Meeting held in Kraków, Poland in May The purpose of the book is to present current ideas, new avenues and research regarding biological functions and clinical applications of taurine and taurine derivatives.

Nine years have elapsed since the second edition of this book was published. In this time the principal advances in neuromuscular diseases have been in the application of molecular genetics to understanding the aetiology and pathogenesis of this group of disorders.

As a result many previously unrecognised disorders have been charac terised. Role of Proteases in Cellular Dysfunction - Ebook written by Naranjan S. Dhalla, Sajal Chakraborti. Read this book using Google Play Books app on your PC, android, iOS devices.

Download for offline reading, highlight, bookmark or take notes while you read Role of Proteases in Cellular Dysfunction.

Completely revised with 15 new chapters, the book includes coverage of the roles of gut microbiome in obesity and diabetes, macrovascular and microvascular complications, diabetes, metabolic syndrome and kidney disease, aspects of diabetic cardiomyopathy, diabetes, Alzheimer's and neurodegenerative diseases, roles of SGLT2 inhibitors in the.

The normal function of the heart relies on a series of complex metabolic processes orchestrating the proper generation and use of energy. In this context, mitochondria serve a crucial role as a platform for energy transduction by supplying ATP to the varying demand of cardiomyocytes, involving an intricate network of pathways regulating the metabolic flux of : Claudia Sacchetto, Vasco Sequeira, Edoardo Bertero, Jan Dudek, Christoph Maack, Martina Calore.

An interpretive report will be provided. When abnormal results are detected, a detailed interpretation is given, including an overview of the results and of their significance, a correlation to available clinical information, elements of differential diagnosis, recommendations for additional biochemical testing, and in vitro confirmatory studies (enzyme assay, molecular analysis).

22) Calabrese, Fiorella, and Gaetano Thiene. “Myocarditis and inflammatory cardiomyopathy: microbiological and molecular biological aspects.” Cardiovascular research (): 23) Triantafilou, Kathy, et al.

“Human cardiac inflammatory responses triggered by Coxsackie B viruses are mainly Toll‐like receptor (TLR) 8‐dependent.”. Cardiomyopathy Reversible with CoQ10 and Selenium by Jeffrey Dach MD. Ischemic Cardiomyopathy. Years ago, when I was working in the hospital as a radiologist, the lab director approached me in the reading room, and asked if I could help with her dad.Completely revised with 15 new chapters, the book includes coverage of the roles of gut microbiome in obesity and diabetes, macrovascular and microvascular complications, diabetes, metabolic syndrome and kidney disease, aspects of diabetic cardiomyopathy, diabetes, Alzheimer’s and neurodegenerative diseases, roles of SGLT2 inhibitors in the Brand: Elsevier Science.Focusing on the dynamic aspects of biochemistry and its application to the basic functions of the body, the book bridges the gap between biochemistry and medical practice.

Carefully structured within five sections, each biochemical, physiological or medical subject that is covered in the book is presented in one complete chapter.